Zika Virus, An Emerging Global Public Health Concern: A Review

  • Smit Shah Rutgers Robert Wood Johnson Medical School
  • Rachana Tyagi Rutgers Robert Wood Johnson University Hospital
  • Margaret Fisher
Keywords: Microcephaly, Aedes aegypti, global transmission


Goal of this article is to present current data from literature review on pathogenesis, transmission, prevention and treatment of Zika Virus (ZIKV). In addition, we also shed light on the latest research in terms of pathogenesis and potential new therapeutic treatment options for children and mothers infected with Zika virus. We performed a literature review of case reports, public health articles, newspaper trade publications, academic journals, review papers, case reports and CDC data from 2001 to 2017 in order to gather adequate information to fulfil the above mentioned goals. We specifically focused on articles: (1) that describe different hypothesis of ZIKV pathogenesis, (2) various mice models used to study ZIKV susceptibility that could be extrapolated to human models, (3) various therapeutic methods and targets that could be used to either prevent the progression or infection of cells from ZIKV and (4) statistics based on the latest prevalence and incidence of ZIKV across different countries including the United States.

Author Biographies

Rachana Tyagi, Rutgers Robert Wood Johnson University Hospital


Margaret Fisher

MD, Department of Infectious Diseases, Monmouth Medical Center, NJ

How to Cite
Shah, S., Tyagi, R., & Fisher, M. (2017). Zika Virus, An Emerging Global Public Health Concern: A Review. International Journal of Perceptions in Public Health, 1(3), 172-176. Retrieved from http://ijpph.org/index.php/ijpph/article/view/59